Whisk flour, baking powder, baking soda, salt, and pumpkin pie spice in a bowl.
Whisk brown sugar, granulated sugar, eggs, pumpkin, and vanilla in a separate bowl, then whisk in the cooled butter.
Fold dry ingredients into wet just until combined. Add up to 2 tbsp more flour if the dough is too loose to hold its shape.
Chill the dough 20-30 minutes.
Scoop into tablespoon-sized balls, roll in granulated sugar then powdered sugar, place 2 inches apart on parchment-lined sheets.
Bake at 350°F for 11-13 minutes until puffed and cracked.
Cool on the pan 10 minutes, then move to a wire rack.